Rotium™ Bioresorbable Wick

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The Rotium™ Bioresorbable Wick is intended to be used in conjunction with suture anchors for the reattachment of tendon to bone in rotator cuff repairs. It is a non-woven, microfiber matrix comprising biodegradable polymer fibers that mimic the extracellular matrix structure. Rotium™ supports cellular infiltration and migration, and facilitates functional tissue regeneration. The Rotium™ Wick is designed to be fully absorbed within 3-4 months over which time it is replaced by neo-native tissue.

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SEM SCANS

Nanofibers act as a scaffold that support cellular ingrowth and proliferation. The Rotium™ Wick supports and encourages the regeneration of healthy tendon and Sharpey fibers.

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HISTORY OF ROTATOR CUFF REPAIR

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  • About 450,000 rotator cuff repairs are performed each year, an increase of 141% in the last decade [1]
  • In the last 30 years there have been tooling improvements, but no healing improvements [2]
  • Some scaffolds have been used as "onlays" but tendon failure occurs at the insertion point and quality of repair is more important than augmenting the tendon [3]
  • "Inlay" scaffolds are currently being investigated, but the four zones of the enthesis are too complex to reproduce in a scaffold [4]
  • There is a need to keep the cells at the repair site to promote healing [5]
  • Our scaffolds have shown the ability to promote cell migration [6], localize cells at the repair site [7], and facilitate remodeling into healthy tissue [8]



This video shows cells migrating along the scaffold material just as they would in the body. An in-vitro study against a prominent competitor showed that Rotium™ outperformed in cell proliferation and adhesion.

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Rotium™ mimics the extracellular matrix found naturally in the body. Our scaffold is engineered to promote healthy tissue growth rather than an inflammatory response - thus decreasing scar tissue formation.

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A medical device company building a line of orthopedic products that provides a structure for improved healing of sports medicine injuries.

Created in partnership with Nanofiber Solutions
Empowered by the IKove Startup Nursery


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